11/28/2023 0 Comments Clone 5 triggers![]() brucei infected adipose tissue revealed that most upregulated host genes are involved in inflammation and immune cell functions. In this study, we tested whether the AT environment responds immunologically to the presence of the parasite. In mice, the gonadal adipose tissue (AT) typically harbors 2–5 million parasites, while most solid organs show 10 to 100-fold fewer parasites. Adipose tissue is one of the major reservoirs of Trypanosoma brucei parasites, the causative agent of sleeping sickness, a fatal disease in humans.
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